Mutates the protein binding peptide region of Stapled peptide PROTAC.
Generate ready-to-use UCSF Chimera Python scripts with desired mutation and optional minimization. Class-wise mode can now produce every combination of selected class members.
Class-wise mode will create a Chimera Python script that iterates over all combinations (cartesian product) of selected amino-acids — one from each class — and writes an output file for each combination. Each iteration re-opens the original structure so changes do not accumulate.